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  • Advert number: 348489-0
  • Posted Date: 16/01/14
  • Closing Date: 28/02/14

University of Dundee

College of Medicine, Dentistry & Nursing

Medical Research Institute
Division of Imaging & Technology


£31,838 - £43,434 per annum

A post is now available for 2 years for a Clinical Research Fellow to perform a Prostate Cancer, UK funded research project. The project will be ideal for an MD Thesis.

The background to the project is as follows. Prostate cancer is the commonest cancer in men and accounts for nearly a quarter (24%) of all new male cancer diagnoses. Men suspected of prostate cancer (elevated serum level of PSA and or abnormal digital rectal examination) are offered transrectal ultrasound (TRUS) guided biopsies to confirm the diagnosis. Due to a lack of a specific sonographic appearance and the multifocal nature of prostate cancer, multiple biopsies are taken under TRUS guidance. In other words, TRUS biopsy is essentially a sampling technique of prostate gland based on systematic biopsy protocols with recommendations that at least ten biopsies should be obtained under local anaesthesia. As with sampling under any circumstance, errors have been reported up to a rate of 20-30%. Moreover, persistently raised prostate specific antigen (PSA) with no evidence of cancer on TRUS-guided biopsies does not exclude possibility of prostate cancer, which poses a real clinical challenge to physicians and causes undue anxiety to patients. Several studies have actually reported poor correlation of histology (Gleason grade and sum) between radical prostatectomy specimen and biopsies results from TRUS. This adds to the clinical dilemma of counselling patients with clinically localised disease for the suitable radical treatment.

Informal enquiries should be directed to Mr Ghulam Nabi (Tel 01382 660111), email We regret that we are unable to accept applications by email.

To apply and for further details please visit our website:

Please quote Reference number MDN0731.

Closing date: 28 February 2014.

The University of Dundee is committed to equal opportunities and welcomes applications from all sections of the community.

The University of Dundee is a Scottish Registered Charity, No. SC015096